Megan Lerner Selected Research

alpha-latrotoxin receptor

4/2021	ELTD1 as a biomarker for multiple sclerosis: Pre-clinical molecular-targeted studies in a mouse experimental autoimmune encephalomyelitis model.
1/2021	ELTD1 as a multi-focal target for malignant gliomas: preclinical studies.
3/2020	Assessment of an scFv Antibody Fragment Against ELTD1 in a G55 Glioblastoma Xenograft Model.
1/2019	Targeting ELTD1, an angiogenesis marker for glioblastoma (GBM), also affects VEGFR2: molecular-targeted MRI assessment.
1/2017	ELTD1, an effective anti-angiogenic target for gliomas: preclinical assessment in mouse GL261 and human G55 xenograft glioma models.

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Megan Lerner Research Topics

Disease

12	Neoplasms (Cancer) 04/2021 - 11/2007
11	Glioma (Gliomas) 01/2021 - 04/2010
6	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 01/2017
3	Coronary Artery Disease (Coronary Atherosclerosis) 01/2022 - 01/2020
3	Pancreatic Neoplasms (Pancreatic Cancer) 03/2011 - 11/2007
2	Inflammation (Inflammations) 04/2021 - 01/2020
2	Interstitial Cystitis (Interstitial Cystitis, Chronic) 01/2020 - 06/2018
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2022
1	Dyslipidemias (Dyslipidemia) 01/2022
1	Multiple Sclerosis 04/2021
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 04/2021
1	Carcinogenesis 01/2021
1	Diffuse Intrinsic Pontine Glioma 11/2020
1	type 1 familial Hypocalciuric hypercalcemia 01/2020
1	Type 2 Diabetes Mellitus (MODY) 01/2020
1	Fibrosis (Cirrhosis) 01/2020
1	Hypercalcemia (Milk Alkali Syndrome) 01/2020
1	Atherosclerosis 01/2020
1	Hypersensitivity (Allergy) 06/2018
1	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 06/2018
1	Wounds and Injuries (Trauma) 01/2017
1	Corneal Injuries 01/2017
1	Alzheimer Disease (Alzheimer's Disease) 10/2015
1	Neuroinflammatory Diseases 10/2015
1	Gliosis 01/2015
1	Blast Injuries 01/2015
1	Necrosis 07/2011
1	Bone Resorption 06/2008
1	Colonic Neoplasms (Colon Cancer) 11/2007
1	Lymphoma (Lymphomas) 11/2007
1	Breast Neoplasms (Breast Cancer) 11/2007
1	Lung Neoplasms (Lung Cancer) 11/2007
1	Chronic Pancreatitis 12/2005

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2015
6	OKN 007IBA 01/2022 - 04/2010
6	Biomarkers (Surrogate Marker)IBA 04/2021 - 01/2017
5	alpha-latrotoxin receptorIBA 04/2021 - 01/2017
5	Epidermal Growth Factor (EGF)IBA 04/2021 - 01/2017
3	LipidsIBA 01/2020 - 07/2011
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2017 - 01/2013
2	Triglycerides (Triacylglycerol)IBA 09/2021 - 04/2012
2	Caspase 3 (Caspase-3)IBA 01/2021 - 11/2020
2	LigandsIBA 01/2020 - 06/2008
2	Immunoglobulin G (IgG)IBA 01/2019 - 09/2017
2	AntibodiesIBA 01/2019 - 01/2017
2	human AZU1 proteinIBA 01/2017 - 10/2015
2	Biotin (Vitamin H)FDA Link 10/2015 - 01/2013
2	Glucose (Dextrose)FDA LinkGeneric 01/2015 - 04/2012
2	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 01/2013 - 04/2011
2	MicroRNAs (MicroRNA)IBA 03/2011 - 11/2007
1	Messenger RNA (mRNA)IBA 01/2022
1	ExoribonucleasesIBA 01/2022
1	Apolipoprotein C-IIIIBA 01/2022
1	RNA (Ribonucleic Acid)IBA 04/2021
1	Single-Chain AntibodiesIBA 01/2021
1	Investigational DrugsIBA 01/2021
1	LDN 193189IBA 11/2020
1	activin AIBA 11/2020
1	Nuclear Antigens (Extractable Nuclear Antigens)IBA 11/2020
1	dipinacoline glutamateIBA 11/2020
1	Histones (Histone)IBA 11/2020
1	Immunoglobulin FragmentsIBA 03/2020
1	Monoclonal AntibodiesIBA 03/2020
1	Parathyroid Hormone (Parathormone)IBA 01/2020
1	Peptides (Polypeptides)IBA 01/2020
1	Claudin-2IBA 01/2020
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2019
1	Protamines (Protamine Sulfate)FDA Link 06/2018
1	CytokinesIBA 01/2017
1	Free RadicalsIBA 10/2015
1	Malondialdehyde (Propanedial)IBA 10/2015
1	Contrast MediaIBA 10/2015
1	AntioxidantsIBA 10/2015
1	albumin-(gadolinium-DTPA)IBA 10/2015
1	3-nitrotyrosineIBA 10/2015
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 10/2015
1	GoldIBA 10/2015
1	salicylhydroxamic acid (SHAM)IBA 01/2015
1	Acetic Acid (Vinegar)FDA LinkGeneric 01/2013
1	diethylenetriamineIBA 01/2013
1	Gadolinium DTPA (Magnevist)FDA Link 01/2013
1	AlbuminsIBA 01/2013
1	PENTAIBA 01/2013
1	Taurine FDA Link 04/2012
1	Choline (Choline Chloride)IBA 04/2012
1	nitronesIBA 07/2011
1	Drinking WaterIBA 07/2011
1	Molecular Probes (Molecular Probe)IBA 04/2011
1	Small Interfering RNA (siRNA)IBA 03/2011
1	Transcription Factors (Transcription Factor)IBA 03/2011
1	Fibroblast Growth Factor 7 FDA Link 08/2009
1	PolyphenolsIBA 06/2008
1	Receptor Activator of Nuclear Factor-kappa B (TRANCE-R)IBA 06/2008
1	Biological ProductsIBA 11/2007
1	Coloring Agents (Dyes)IBA 12/2005
1	Formaldehyde (Formol)FDA Link 12/2005
1	Membrane Glycoproteins (Membrane Glycoprotein)IBA 12/2005

Therapy/Procedure

8	Therapeutics 01/2022 - 07/2011
1	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2020
1	Intravenous Administration 01/2013